<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/">
<rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/558">
    <dcterms:title><![CDATA[A Comprehensive Renewable and Sustainable Energy Policy for Jamaica]]></dcterms:title>
    <dcterms:subject><![CDATA[Renewable energy sources--Jamaica.<br />
Renewable natural resources--Jamaica.<br />
Power resources--Jamaica.]]></dcterms:subject>
    <dcterms:creator><![CDATA[Fox, Robert L]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology]]></dcterms:publisher>
    <dcterms:date><![CDATA[2009]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a href="https://repository.nyitlibrary.org/files/original/b9c8bd162010fa75b334eba7129e4e27.pdf">https://repository.nyitlibrary.org/files/original/b9c8bd162010fa75b334eba7129e4e27.pdf</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/2207">
    <dcterms:title><![CDATA[Electric Vehicles : an Environmental Impact Analysis]]></dcterms:title>
    <dcterms:creator><![CDATA[Fracassi, George P.]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology.]]></dcterms:publisher>
    <dcterms:date><![CDATA[1999]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Thesis (M.S.)--New York Institute of Technology]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a href="https://repository.nyitlibrary.org/files/original/28ed48020f9ee6d38764afa98365a000.pdf">https://repository.nyitlibrary.org/files/original/28ed48020f9ee6d38764afa98365a000.pdf</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/3798">
    <dcterms:title><![CDATA[The Cultural Construction of the Domestic Space in France: Women’s Lived Experience and the Materialization of Customs]]></dcterms:title>
    <dcterms:abstract><![CDATA[This article explores the intersecting processes of construction of the home, social, and individual identities through domestic practices inside French housing. It examines the design and occupation of French homes as crucial moments for the consolidation of subjectivities, beliefs, and ideologies manifested through daily actions that are influenced by normative cultural systems. In specific, it looks at codified domestic behaviours and their aesthetic dimension, focusing on how the French “art of living” has influenced taste, design, appropriation, and decoration of domestic interiors. Architectural treatises along with etiquette manuals are analysed as they both represent—through the written word and architectural drawings—cultural and gender stereotypes as well as societal norms and expectations that inform housing design and domestic practices. These documents directly assist in the cultural construction of the domestic space, uncovering mechanisms of reproduction and representation that inform the use and design of residential architecture. By focusing on women’s lived experiences, this research looks at the consolidation of feminine domestic cultures and how they fostered small-scale physical transformations of dwellings’ interiors through daily negotiations that define self-identity and interpersonal power relations. These dynamics are referred to as “cultural domesticity.” The latter frames this study along with feminist literature, situating women’s contribution to the aesthetic and spatial development of French apartments. What emerges from this study is that the French state historically exercised a regulatory power that impacted daily life and housing design.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[Francesca Forlini]]></dcterms:creator>
    <dcterms:source><![CDATA[ Vol 9 (2024): Housing Norms and Standards: The Design of Everyday Life]]></dcterms:source>
    <dcterms:date><![CDATA[2024]]></dcterms:date>
    <dcterms:rights><![CDATA[ Francesca Romana Forlini. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 license (http://creativecommons.org/licenses/by/4.0), which permits any use, distribution, and reproduction of the work without further permission provided the original author(s) and source are credited.]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:identifier><![CDATA[<span class="linkify-target internal-link">https://repository.nyitlibrary.org/files/original/eea5c1ac61a432a0f8d1785771d2d49d.pdf</span>]]></dcterms:identifier>
    <dcterms:identifier><![CDATA[<a href="https://doi.org/10.17645/up.7753">https://doi.org/10.17645/up.7753</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/3927">
    <dcterms:title><![CDATA[Newsday newspaper plant : an in depth study of industrial plant design]]></dcterms:title>
    <dcterms:subject><![CDATA[Newsday<br />
Factories—Design and construction]]></dcterms:subject>
    <dcterms:creator><![CDATA[Francis, Bernard J.]]></dcterms:creator>
    <dcterms:publisher><![CDATA[Old Westbury, N.Y. : New York Institute of Technology, 1979.]]></dcterms:publisher>
    <dcterms:date><![CDATA[1979]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Thesis (Bachelor&#039;s)--New York Institute of Technology, 1979.]]></dcterms:type>
    <dcterms:identifier><![CDATA[<span class="linkify-target internal-link">https://repository.nyitlibrary.org/files/original/3feb36b6fca631b7d0f9bcccda6eb0a4.pdf</span>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/1537">
    <dcterms:title><![CDATA[Electric motors and their efficiencies.]]></dcterms:title>
    <dcterms:subject><![CDATA[ Electric motors--Energy consumption. <br />
Electric power--Conservation.]]></dcterms:subject>
    <dcterms:creator><![CDATA[Francis, Franklin.]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology]]></dcterms:publisher>
    <dcterms:date><![CDATA[2000]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<span class="linkify-target internal-link">https://repository.nyitlibrary.org/files/original/7e06d1225805b802216f1b4a0a8b8a11.pdf</span>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/140">
    <dcterms:title><![CDATA[Sustainable Design of a 1-Bedroom/Single Family House in the Caribbean ]]></dcterms:title>
    <dcterms:subject><![CDATA[Sustainable Architecture--Designs and plans.<br />
Dwellings--Design and construction.<br />
Architecture, Domestic--Caribbean Area.]]></dcterms:subject>
    <dcterms:creator><![CDATA[Francis, Kahlil Q]]></dcterms:creator>
    <dcterms:publisher><![CDATA[Old Westbury, N.Y. : New York Institute of Technology, 2015.]]></dcterms:publisher>
    <dcterms:date><![CDATA[2015]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<span class="linkify-target internal-link">https://repository.nyitlibrary.org/files/original/38e7ffa300176b1735ceab75267e1165.pdf</span>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/740">
    <dcterms:title><![CDATA[Problem Solving Strategies During Disputes: Mediation Skills for Police Recruits]]></dcterms:title>
    <dcterms:creator><![CDATA[Francis, Richard Allen]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology]]></dcterms:publisher>
    <dcterms:date><![CDATA[1992]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a href="https://repository.nyitlibrary.org/files/original/a87e8c811008fb46d98cdae7e317cb5a.pdf">https://repository.nyitlibrary.org/files/original/a87e8c811008fb46d98cdae7e317cb5a.pdf</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/559">
    <dcterms:title><![CDATA[Hybrid Electric Vehicles : A Technical and Environmental Evaluation]]></dcterms:title>
    <dcterms:creator><![CDATA[Francone, Dominick]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology]]></dcterms:publisher>
    <dcterms:date><![CDATA[1996]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a href="https://repository.nyitlibrary.org/files/original/1b565ba1e14611e9df2ae0adc72e64bd.pdf">https://repository.nyitlibrary.org/files/original/1b565ba1e14611e9df2ae0adc72e64bd.pdf</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/4273">
    <dcterms:title><![CDATA[Park side sports facility]]></dcterms:title>
    <dcterms:subject><![CDATA[Sports facilities]]></dcterms:subject>
    <dcterms:creator><![CDATA[Frank E Del Giudice]]></dcterms:creator>
    <dcterms:publisher><![CDATA[Old Westbury, N.Y. : New York Institute of Technology, 1996]]></dcterms:publisher>
    <dcterms:date><![CDATA[1996]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Thesis (Bachelor&#039;s)--New York Institute of Technology, 1996]]></dcterms:type>
    <dcterms:identifier><![CDATA[<span class="linkify-target internal-link">https://repository.nyitlibrary.org/files/original/9ff0d64bf2bd6b1512c6aaf8c37f994f.pdf</span>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/1855">
    <dcterms:title><![CDATA[The Impact and Significance That Mergers, Acquisitions and Leveraged Buyouts Have on the Food Industry]]></dcterms:title>
    <dcterms:subject><![CDATA[Consolidation and merger of corporations.<br />
Food industry and trade--Consolidation.]]></dcterms:subject>
    <dcterms:creator><![CDATA[Frank, Martin O]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology]]></dcterms:publisher>
    <dcterms:date><![CDATA[1990]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a href="https://repository.nyitlibrary.org/files/original/e2eba3c93ac76d6ee074bfca2fa7f75e.pdf">https://repository.nyitlibrary.org/files/original/e2eba3c93ac76d6ee074bfca2fa7f75e.pdf</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/1066">
    <dcterms:title><![CDATA[Using Motivational Techniques and Incentives to Increase Employee Productivity and Reduce Employee Turnovers.]]></dcterms:title>
    <dcterms:subject><![CDATA[Incentives in industry.<br />
Labor productivity.<br />
Labor turnover.]]></dcterms:subject>
    <dcterms:creator><![CDATA[Frank, Susan C.]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology]]></dcterms:publisher>
    <dcterms:date><![CDATA[1990]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<span class="linkify-target internal-link">https://repository.nyitlibrary.org/files/original/d1dfdda34bdb5ff0b8eccf28ae219a08.pdf</span>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/2793">
    <dcterms:title><![CDATA[Will the Health Insurance Portability and Accountability Act of 1996 Be Effective in Protecting Patients&#039; Privacy?]]></dcterms:title>
    <dcterms:subject><![CDATA[Data protection - Law and legislation - United States<br />
Medical records - Access control - United States]]></dcterms:subject>
    <dcterms:creator><![CDATA[Franklin, Deborah E.]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology.]]></dcterms:publisher>
    <dcterms:date><![CDATA[2003]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:identifier><![CDATA[<a href="https://repository.nyitlibrary.org/files/original/bbf7ac0dfd0db3379dd6eb8bfd89d695.pdf" target="_blank" title="Will the Health Insurance Portability and Accountability Act of 1996 Be Effective in Protecting Patients' Privacy?" rel="noreferrer noopener">https://repository.nyitlibrary.org/files/original/bbf7ac0dfd0db3379dd6eb8bfd89d695.pdf</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/1854">
    <dcterms:title><![CDATA[Physical Security : Cost Versus Security]]></dcterms:title>
    <dcterms:subject><![CDATA[security systems.<br />
Corporations--Security measures.<br />
Security systems.]]></dcterms:subject>
    <dcterms:creator><![CDATA[Franklyn, Brian E.]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology]]></dcterms:publisher>
    <dcterms:date><![CDATA[1991]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a href="https://repository.nyitlibrary.org/files/original/31ec37fd2054e90f3e80a8e47315a292.pdf">https://repository.nyitlibrary.org/files/original/31ec37fd2054e90f3e80a8e47315a292.pdf</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/3707">
    <dcterms:title><![CDATA[Support for osteopathic manipulative treatment inclusion in chronic pain management guidelines: a narrative review]]></dcterms:title>
    <dcterms:subject><![CDATA[Chronic Pain therapy<br />
Humans<br />
Index Medicus<br />
Low Back Pain<br />
Manipulation, Osteopathic<br />
Pain Management<br />
Treatment Outcome]]></dcterms:subject>
    <dcterms:abstract><![CDATA[<h4 class="subheading">Context</h4>
<p>Osteopathic manipulative treatment (OMT) is used to treat chronic pain conditions. However, few guidelines focusing on chronic pain management include recommendations for OMT.</p>
<h4 class="subheading">Objectives</h4>
<p>To evaluate previous literature on the use of OMT for improving chronic pain.</p>
<h4 class="subheading">Methods</h4>
<p>A literature search was conducted on MEDLINE/PubMed and ScienceDirect on August 26–27, 2019, using the terms “osteopathic,” “chronic,” and “pain,” yielding a total of 312 MEDLINE/PubMed articles and 515 ScienceDirect articles. Eligibility criteria required that studies investigate pain, functional status, or medication usage through an experimental design, focusing on human subjects with chronic pain who had various forms of OMT administered by osteopathically trained individuals in which the comparator group received no intervention, a sham or placebo, or conventional care. Three authors independently performed literature searches and methodically settled disagreements over article selection.</p>
<h4 class="subheading">Results</h4>
<p>In the 22 articles included in our study that examined OMT use in chronic pain conditions, we evaluated primary outcomes of pain (22; 100%) and functional status (20; 90.9%), and the secondary outcome of medication usage (3; 13.6%). The majority of articles showed that OMT resulted in a significant decrease in pain levels as compared to baseline pain levels or the control group (20; 90.9%) and that OMT resulted in an improvement in functional status (17; 77.3%). In articles that did not find a significant difference in pain (2; 9.1%) or functional status (3; 13.6%), there were overall outcomes improvements noted. All articles that investigated medication usage (3; 13.6%) showed that OMT was effective in decreasing patients’ medication usage. Our study was limited by its small sample size and multimodal comparator group exclusion.</p>
<h4 class="subheading">Conclusions</h4>
<p>OMT provides an evidence-based management option to reduce pain levels, improve functional status, and decrease medication usage in chronic pain conditions, especially low back pain (LBP). Pain management guidelines should include OMT as a resource to alleviate chronic pain.</p>]]></dcterms:abstract>
    <dcterms:creator><![CDATA[Franzetti, M., Dries, E., Stevens, B., Berkowitz, L., &amp; Yao, S. C.]]></dcterms:creator>
    <dcterms:source><![CDATA[<em>Journal of Osteopathic Medicine</em>, Volume 121, Issue 3, February 2021, pages 307-317]]></dcterms:source>
    <dcterms:publisher><![CDATA[Walter de Gruyter GmbH]]></dcterms:publisher>
    <dcterms:date><![CDATA[2021]]></dcterms:date>
    <dcterms:rights><![CDATA[© 2020 Megan Franzetti et al., published by De Gruyter, Berlin/Boston<br />
This work is licensed under the Creative Commons Attribution 4.0 International License.]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a href="https://repository.nyitlibrary.org/files/original/a22e1fa244f0c6fdc0c731c37505d7fd.pdf">https://repository.nyitlibrary.org/files/original/a22e1fa244f0c6fdc0c731c37505d7fd.pdf<br /><br /></a>]]></dcterms:identifier>
    <dcterms:identifier><![CDATA[<a href="https://doi.org/10.1515/jom-2019-0284">https://doi.org/10.1515/jom-2019-0284</a>]]></dcterms:identifier>
    <dcterms:bibliographicCitation><![CDATA[<span>Franzetti, M., Dries, E., Stevens, B., Berkowitz, L., &amp; Yao, S. C. (2021). Support for osteopathic manipulative treatment inclusion in chronic pain management guidelines: a narrative review. In Journal of Osteopathic Medicine (Vol. 121, Issue 3, pp. 307–317). Walter de Gruyter GmbH. <a href="https://doi.org/10.1515/jom-2019-0284">https://doi.org/10.1515/jom-2019-0284</a></span>]]></dcterms:bibliographicCitation>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/2540">
    <dcterms:title><![CDATA[The Feasibility of the Diversification of the Not-for-Profit Hospital Into Alternate Health Care Delivery Systems]]></dcterms:title>
    <dcterms:creator><![CDATA[Franzoni, Camille]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology]]></dcterms:publisher>
    <dcterms:date><![CDATA[1992]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Thesis (M.S.)--New York Institute of Technology]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a href="https://repository.nyitlibrary.org/files/original/476bedd48a2cfa06535bdb4dbecd62d1.pdf">https://repository.nyitlibrary.org/files/original/476bedd48a2cfa06535bdb4dbecd62d1.pdf</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/560">
    <dcterms:title><![CDATA[Power Plant Cogeneration at Sikorsky Aircraft]]></dcterms:title>
    <dcterms:subject><![CDATA[Cogeneration of electric power and heat.<br />
Steam power plants.]]></dcterms:subject>
    <dcterms:creator><![CDATA[Fraschilla, Angelo]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology]]></dcterms:publisher>
    <dcterms:date><![CDATA[2007]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<a href="https://repository.nyitlibrary.org/files/original/5bea921e9f5959408a630d19703ab4e4.pdf">https://repository.nyitlibrary.org/files/original/5bea921e9f5959408a630d19703ab4e4.pdf</a>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/4221">
    <dcterms:title><![CDATA[Proxemics : the cultural aspects of privacy and community]]></dcterms:title>
    <dcterms:subject><![CDATA[Space (Architecture)]]></dcterms:subject>
    <dcterms:subject><![CDATA[Privacy]]></dcterms:subject>
    <dcterms:creator><![CDATA[Fraser, Betty]]></dcterms:creator>
    <dcterms:publisher><![CDATA[Old Westbury, N.Y. :New York Institute of Technology,1981.]]></dcterms:publisher>
    <dcterms:date><![CDATA[1981]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Thesis (Bachelor&#039;s)--New York Institute of Technology, 1981]]></dcterms:type>
    <dcterms:identifier><![CDATA[<span class="linkify-target internal-link">https://repository.nyitlibrary.org/files/original/d5b4f6f8f08549844b7820c38ec40166.pdf</span>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/1598">
    <dcterms:title><![CDATA[Industrial safety within the Metropolitan Transportation Authority&#039;s Long Island bus system.]]></dcterms:title>
    <dcterms:creator><![CDATA[Fraser, Troy.]]></dcterms:creator>
    <dcterms:publisher><![CDATA[New York Institute of Technology]]></dcterms:publisher>
    <dcterms:date><![CDATA[1998]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<span class="linkify-target internal-link">https://repository.nyitlibrary.org/files/original/fd174ccd17519c0d1bfcaf867b9d6dd8.pdf</span>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/3976">
    <dcterms:title><![CDATA[Educational institution for behaviorally &amp; emotionally disturbed adolescents]]></dcterms:title>
    <dcterms:subject><![CDATA[Barrier-free design for children with mental disabilities<br />
Architecture—Designs and plans]]></dcterms:subject>
    <dcterms:creator><![CDATA[Fredrickson, James R.]]></dcterms:creator>
    <dcterms:publisher><![CDATA[Old Westbury, N.Y. : New York Institute of Technology]]></dcterms:publisher>
    <dcterms:date><![CDATA[1995]]></dcterms:date>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Thesis (Bachelor&#039;s)--New York Institute of Technology]]></dcterms:type>
    <dcterms:identifier><![CDATA[<span class="linkify-target internal-link">https://repository.nyitlibrary.org/files/original/0c053df913a2a062491ff7de65f5fc97.pdf</span>]]></dcterms:identifier>
</rdf:Description><rdf:Description rdf:about="https://repository.nyitlibrary.org/items/show/3787">
    <dcterms:title><![CDATA[Pre-clinical safety and therapeutic efficacy of a plant-based alkaloid in a human colon cancer xenograft model]]></dcterms:title>
    <dcterms:subject><![CDATA[Drug development<br />
Drug safety]]></dcterms:subject>
    <dcterms:abstract><![CDATA[A high-throughput drug screen revealed that veratridine (VTD), a natural plant alkaloid, induces expression of the anti-cancer protein UBXN2A in colon cancer cells. UBXN2A suppresses mortalin, a heat shock protein, with dominant roles in cancer development including epithelial-mesenchymal transition (EMT), cancer cell stemness, drug resistance, and apoptosis. VTD-dependent expression of UBXN2A leads to the deactivation of mortalin in colon cancer cells, making VTD a potential targeted therapy in malignant tumors with high levels of mortalin. VTD was used clinically for the treatment of hypertension in decades past. However, the discovery of newer antihypertensive drugs and concerns over potential neuro- and cardiotoxicity ended the use of VTD for this purpose. The current study aims to determine the safety and efficacy of VTD at doses sufficient to induce UBXN2A expression in a mouse model. A set of flow-cytometry experiments confirmed that VTD induces both early and late apoptosis in a dose-dependent manner. In vivo intraperitoneal (IP) administration of VTD at 0.1 mg/kg every other day (QOD) for 4 weeks effectively induced expression of UBXN2A in the small and large intestines of mice. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) assays on tissues collected from VTD-treated animals demonstrated VTD concentrations in the low pg/mg range. To address concerns regarding neuro- and cardiotoxicity, a comprehensive set of behavioral and cardiovascular assessments performed on C57BL/6NHsd mice revealed that VTD generates no detectable neurotoxicity or cardiotoxicity in animals receiving 0.1 mg/kg VTD QOD for 30 days. Finally, mouse xenograft experiments in athymic nude mice showed that VTD can suppress tumor growth. The main causes for the failure of experimental oncologic drug candidates are lack of sufficient safety and efficacy. The results achieved in this study support the potential utility of VTD as a safe and efficacious anti-cancer molecule.]]></dcterms:abstract>
    <dcterms:creator><![CDATA[Freeling, J. L., Scholl, J. L., Eikanger, M., Knoblich, C., Potts, R. A., Anderson, D. J., Rower, J. E., Farjoo, M. H., Zhao, H., Pillatzki, A., &amp; Rezvani, K.]]></dcterms:creator>
    <dcterms:source><![CDATA[<i>Cell Death Discovery</i><span>, Volume 8, Issue 1, March 2022</span>]]></dcterms:source>
    <dcterms:publisher><![CDATA[Springer Science and Business Media LLC]]></dcterms:publisher>
    <dcterms:date><![CDATA[2022]]></dcterms:date>
    <dcterms:rights><![CDATA[<b>Open Access</b><span> This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third-party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit </span><a href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</a><span>.</span>]]></dcterms:rights>
    <dcterms:format><![CDATA[PDF]]></dcterms:format>
    <dcterms:language><![CDATA[English]]></dcterms:language>
    <dcterms:type><![CDATA[Text]]></dcterms:type>
    <dcterms:identifier><![CDATA[<span class="linkify-target internal-link">https://repository.nyitlibrary.org/files/original/0f3bc12089774adc10ecddcd37e4a624.pdf</span>]]></dcterms:identifier>
    <dcterms:identifier><![CDATA[<a href="https://doi.org/10.1038/s41420-022-00936-3">https://doi.org/10.1038/s41420-022-00936-3</a>]]></dcterms:identifier>
    <dcterms:bibliographicCitation><![CDATA[<span>Freeling, J. L., Scholl, J. L., Eikanger, M., Knoblich, C., Potts, R. A., Anderson, D. J., Rower, J. E., Farjoo, M. H., Zhao, H., Pillatzki, A., &amp; Rezvani, K. (2022). Pre-clinical safety and therapeutic efficacy of a plant-based alkaloid in a human colon cancer xenograft model. In Cell Death Discovery (Vol. 8, Issue 1). Springer Science and Business Media LLC. <a href="https://doi.org/10.1038/s41420-022-00936-3">https://doi.org/10.1038/s41420-022-00936-3</a></span>]]></dcterms:bibliographicCitation>
</rdf:Description></rdf:RDF>
