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                <text>Background. Non-motor symptoms of Parkinson’s disease (PD) such as cognitive impairment are common and decrease patient quality of life and daily functioning. While no pharmacological treatments have effectively alleviated these symptoms to date, non-pharmacological approaches such as cognitive remediation therapy (CRT) and physical exercise have both been shown to improve cognitive function and quality of life in people with PD. Objective. This study aims to determine the feasibility and impact of remote CRT on cognitive function and quality of life in patients with PD participating in an organized group exercise program. Methods. Twenty-four subjects with PD recruited from Rock Steady Boxing (RSB), a non-contact group exercise program, were evaluated using standard neuropsychological and quality of life measures and randomized to the control or intervention group. The intervention group attended online CRT sessions for one hour, twice a week for 10 weeks, engaging in multi-domain cognitive exercises and group discussion. Results. Twenty-one subjects completed the study and were reevaluated. Comparing groups over time, the control group (n = 10) saw a decline in overall cognitive performance that trended towards significance () and a statistically significant decrease in delayed memory () and self-reported cognition (). Neither of these findings were seen in the intervention group (n = 11), which overwhelmingly enjoyed the CRT sessions and attested to subjective improvements in their daily lives. Conclusions. This randomized controlled pilot study suggests that remote CRT for PD patients is feasible, enjoyable, and may help slow the progression of cognitive decline. Further trials are warranted to determine the longitudinal effects of such a program.</text>
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                <text>Hoffman, L., Burt, N. D., Piniella, N. R., Baker, M., Volino, N., Yasin, S., Jung, M.-K., Leder, A., &amp; Sousa, A. (2023). Efficacy and Feasibility of Remote Cognitive Remediation Therapy in Parkinson’s Disease: A Randomized Controlled Trial. In G. Mirabella (Ed.), Parkinson’s Disease (Vol. 2023, pp. 1–10). Hindawi Limited. https://doi.org/10.1155/2023/6645554</text>
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                <text>&lt;div class="abstract"&gt;
&lt;h4 class="subheading"&gt;Context&lt;/h4&gt;
&lt;p&gt;Parkinson’s disease (PD) is a neurodegenerative disease that leads to impaired motor and non-motor function in patients. PD is non-curative and gradually reduces quality of life, leading patients to seek treatment for symptom management. Osteopathic manipulative treatment (OMT) applies the biomechanical, neurologic, circulatory, metabolic, and psychosocial models in approaching and treating the major symptomatology of PD patients.&lt;/p&gt;
&lt;h4 class="subheading"&gt;Objectives&lt;/h4&gt;
&lt;p&gt;This article evaluates the literature published in the past 10 years analyzing evidence on OMT and its functional application on gait, balance, motor function, bradykinesia, and autonomic dysfunctions, and to identify promising avenues for further investigation.&lt;/p&gt;
&lt;h4 class="subheading"&gt;Methods&lt;/h4&gt;
&lt;p&gt;The authors obtained studies from the research databases MEDLINE/PubMed, ScienceDaily, and EBSCO, as well as the&lt;span&gt; &lt;/span&gt;&lt;em&gt;Journal of American Osteopathic Association’s&lt;/em&gt;&lt;span&gt; &lt;/span&gt;published archives. Searches were conducted in December 2020 utilizing the search phrases “OMM” (osteopathic manipulative medicine), “OMT,” “osteopathic,” “Parkinson Disease,” “manual therapy,” “physical therapy,” “training,” “autonomics,” “gait,” and “balance.” Articles published between 2010 and 2021 including subjects with Parkinson’s disease and the use of OMT or any other form of manual therapy were included. Five authors independently performed literature searches and methodically resolved any disagreements over article selection together.&lt;/p&gt;
&lt;h4 class="subheading"&gt;Results&lt;/h4&gt;
&lt;p&gt;There were a total of 10,064 hits, from which 53 articles were considered, and five articles were selected based on the criteria.&lt;/p&gt;
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&lt;p&gt;The progressive nature of PD places symptom management on the forefront of maintaining patients’ quality of life. OMT has demonstrated the greatest efficacy on managing motor-related and neurologic symptoms and assists in treating the greater prevalence of somatic dysfunctions that arise from the disease. Research in this field remains limited and should be the target of future research.&lt;/p&gt;
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