1 20 3290 https://repository.nyitlibrary.org/files/original/5bb8167e248f2285e5be265a96007bd0.pdf 49f098703adbdda79e2145d1817170a2 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource NYITCOM - Faculty Publications Publication Book or Journal Article published by New York Tech Facility. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource β-Adrenergic Receptor Desensitization/Down-Regulation in Heart Failure: A Friend or Foe? Identifier An unambiguous reference to the resource within a given context <a href="https://repository.nyitlibrary.org/files/original/5bb8167e248f2285e5be265a96007bd0.pdf">https://repository.nyitlibrary.org/files/original/5bb8167e248f2285e5be265a96007bd0.pdf </a> <a href="http://doi.org/10.3389/fcvm.2022.925692">http://doi.org/10.3389/fcvm.2022.925692</a> Creator An entity primarily responsible for making the resource Mahmood, A., Ahmed, K., & Zhang, Y. Date A point or period of time associated with an event in the lifecycle of the resource 2022 Publisher An entity responsible for making the resource available Frontiers Media SA Subject The topic of the resource Diseases of the circulatory (Cardiovascular) system Arrhythmia Calcium leak Cardiac ryanodine receptor Heart failure β-adrenergic receptor β-adrenergic receptor desensitization/down-regulation Language A language of the resource English Rights Information about rights held in and over the resource Copyright © 2022 Mahmood, Ahmed and Zhang. This is an open-access article distributed under the terms of the <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank" rel="noreferrer noopener">Creative Commons Attribution License (CC BY)</a>. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Source A related resource from which the described resource is derived Frontiers in Cardiovascular Medicine, Volume 9, July 2022 Format The file format, physical medium, or dimensions of the resource PDF Abstract A summary of the resource. Cardiac sympathetic activation, mediated by β-adrenergic receptors (β-ARs), normally increases cardiac contraction and relaxation. Accomplishing this task requires a physiological, concerted Ca2+ signaling, being able to increase Ca2+ release from sarcoplasmic reticulum (SR) in systole and speed up Ca2+ re-uptake in diastole. In heart failure (HF) myocardial β-ARs undergo desensitization/down-regulation due to sustained sympathetic adrenergic activation. β-AR desensitization/down-regulation diminishes adrenergic signaling and cardiac contractile reserve, and is conventionally considered to be detrimental in HF progression. Abnormal Ca2+ handling, manifested as cardiac ryanodine receptor (RyR2) dysfunction and diastolic Ca2+ leak (due to sustained adrenergic activation) also occur in HF. RyR2 dysfunction and Ca2+ leak deplete SR Ca2+ store, diminish Ca2+ release in systole and elevate Ca2+ levels in diastole, impairing both systolic and diastolic ventricular function. Moreover, elevated Ca2+ levels in diastole promote triggered activity and arrhythmogenesis. In the presence of RyR2 dysfunction and Ca2+ leak, further activation of the β-AR signaling in HF would worsen the existing abnormal Ca2+ handling, exacerbating not only cardiac dysfunction, but also ventricular arrhythmogenesis and sudden cardiac death. Thus, we conclude that β-AR desensitization/down-regulation may be a self-preserving, adaptive process (acting like an intrinsic β-AR blocker) protecting the failing heart from developing lethal ventricular arrhythmias under conditions of elevated sympathetic drive and catecholamine levels in HF, rather than a conventionally considered detrimental process. This also implies that medications simply enhancing β-AR signaling (like β-AR agonists) may not be so beneficial unless they can also correct dysfunctional Ca2+ handling in HF. Type The nature or genre of the resource Text Bibliographic Citation A bibliographic reference for the resource. Recommended practice is to include sufficient bibliographic detail to identify the resource as unambiguously as possible. Mahmood, A., Ahmed, K., & Zhang, Y. (2022). β-Adrenergic Receptor Desensitization/Down-Regulation in Heart Failure: A Friend or Foe? In Frontiers in Cardiovascular Medicine (Vol. 9). Frontiers Media SA. <a href="https://doi.org/10.3389/fcvm.2022.925692">https://doi.org/10.3389/fcvm.2022.925692</a> https://repository.nyitlibrary.org/files/original/bb3034f33371c843e8544295206b6ec1.pdf eea24b4625ca44bbe5e1742e3e6e40a5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Energy Management - Dissertations & Theses Thesis A long essay or dissertation involving personal research, written by a candidate for a college degree. School School of Engineering and Computing Sciences Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Zero Energy Buildings Creator An entity primarily responsible for making the resource Uppala, Kavya Date A point or period of time associated with an event in the lifecycle of the resource 2015 Publisher An entity responsible for making the resource available New York Institute of Technology Subject The topic of the resource Sustainable architecture. Energy conservation. Renewable energy sources. Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context <a href="https://repository.nyitlibrary.org/files/original/bb3034f33371c843e8544295206b6ec1.pdf">https://repository.nyitlibrary.org/files/original/bb3034f33371c843e8544295206b6ec1.pdf</a> Energy Management Thesis https://repository.nyitlibrary.org/files/original/4868ce8bf90f757033e5797f940aa8cb.pdf a93a3cceef3756eeb321a518b14e2228 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Architecture & Design - Dissertations & Theses Thesis A long essay or dissertation involving personal research, written by a candidate for a college degree. School School of Architecture & Design Department Department of Architecture Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Creator An entity primarily responsible for making the resource Dowd, Richard Title A name given to the resource Zahn's Airport redevelopment program : design proposal Date A point or period of time associated with an event in the lifecycle of the resource 1979 Publisher An entity responsible for making the resource available Old Westbury, N.Y. : New York Institute of Technology, 1979. 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School School of Architecture & Design Department Department of Architecture Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Yonkers criminal courthouse Identifier An unambiguous reference to the resource within a given context https://repository.nyitlibrary.org/files/original/ec5007a7a7ab06fbcb3151143b38ac73.pdf Creator An entity primarily responsible for making the resource Korwatch, James Date A point or period of time associated with an event in the lifecycle of the resource 1996 Publisher An entity responsible for making the resource available Old Westbury, N.Y. : New York Institute of Technology, 1996. Subject The topic of the resource Courthouses—New York (State)—Yonkers—Designs and plans Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Thesis (Bachelor's)--New York Institute of Technology, 1996 https://repository.nyitlibrary.org/files/original/009a254b8938e97ff6a6be1e32dfefe7.pdf 1906be2a8a524ac0673b49693cf2dec4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Architecture & Design - Dissertations & Theses Thesis A long essay or dissertation involving personal research, written by a candidate for a college degree. School School of Architecture & Design Department Department of Architecture Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource YMCA Identifier An unambiguous reference to the resource within a given context https://repository.nyitlibrary.org/files/original/009a254b8938e97ff6a6be1e32dfefe7.pdf Creator An entity primarily responsible for making the resource Hatzmann, Kirk C. Date A point or period of time associated with an event in the lifecycle of the resource 1996 Publisher An entity responsible for making the resource available Old Westbury, N.Y. : New York Institute of Technology Subject The topic of the resource Recreation centers Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Thesis (Bachelor's)--New York Institute of Technology, 1996 https://repository.nyitlibrary.org/files/original/3db6bde66a42cbd1662919d92d581eba.pdf bd7e7e27891fd56aacb085d39a0b0a2f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Business Administration - Dissertations & Theses Thesis A long essay or dissertation involving personal research, written by a candidate for a college degree. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Yam-Burger Goes Public Creator An entity primarily responsible for making the resource Cohen, Raanan Date A point or period of time associated with an event in the lifecycle of the resource 1994 Publisher An entity responsible for making the resource available New York Institute of Technology Subject The topic of the resource Hamburgers--Marketing. Meat substitutes--Marketing. Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context <a href="https://repository.nyitlibrary.org/files/original/3db6bde66a42cbd1662919d92d581eba.pdf">https://repository.nyitlibrary.org/files/original/3db6bde66a42cbd1662919d92d581eba.pdf</a> https://repository.nyitlibrary.org/files/original/0e7ff0471b73f65de824e87c2eebbe57.pdf 731539ec69ecf19f374f966e90230077 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clinical Nutrition - Dissertations & Theses Thesis A long essay or dissertation involving personal research, written by a candidate for a college degree. 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Title A name given to the resource Xerostomia : An Investigation of Its Effect on Dietary Intake Publisher An entity responsible for making the resource available New York Institute of Technology Language A language of the resource English Salivary glands Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Thesis (M.S.)--New York Institute of Technology Creator An entity primarily responsible for making the resource Rover, Rita Date A point or period of time associated with an event in the lifecycle of the resource 1987 Subject The topic of the resource Nutrition Identifier An unambiguous reference to the resource within a given context <a href="https://repository.nyitlibrary.org/files/original/0e7ff0471b73f65de824e87c2eebbe57.pdf" target="_blank" title="Xerostomia : An Investigation of Its Effect on Dietary Intake" rel="noreferrer noopener">https://repository.nyitlibrary.org/files/original/0e7ff0471b73f65de824e87c2eebbe57.pdf</a> Health Nutrition Thesis https://repository.nyitlibrary.org/files/original/525c970f087f4becdba39f87215075b5.pdf 731539ec69ecf19f374f966e90230077 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. 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Title A name given to the resource Xerostomia : An Investigation of Its Effect on Dietary Intake Creator An entity primarily responsible for making the resource Rover, Rita Date A point or period of time associated with an event in the lifecycle of the resource 1987 Publisher An entity responsible for making the resource available New York Institute of Technology Subject The topic of the resource Nutrition Salivary glands Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Thesis (M.S.)--New York Institute of Technology Identifier An unambiguous reference to the resource within a given context <a href="https://repository.nyitlibrary.org/files/original/525c970f087f4becdba39f87215075b5.pdf">https://repository.nyitlibrary.org/files/original/525c970f087f4becdba39f87215075b5.pdf</a> Health Nutrition Thesis https://repository.nyitlibrary.org/files/original/5ab622be6d672893198c7cd9437e7ca5.pdf 2192698edfc4384ef09a884bc820b7b7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. 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Title A name given to the resource Writing a Personal Narrative Through the Writing Workshop Designed for Sixth Grade At-Risk Students Creator An entity primarily responsible for making the resource Reed, Gayle Marie Date A point or period of time associated with an event in the lifecycle of the resource 1990 Publisher An entity responsible for making the resource available New York Institute of Technology Subject The topic of the resource Composition (Language arts)--Study and teaching (Elementary) Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context <a href="https://repository.nyitlibrary.org/files/original/5ab622be6d672893198c7cd9437e7ca5.pdf">https://repository.nyitlibrary.org/files/original/5ab622be6d672893198c7cd9437e7ca5.pdf</a> https://repository.nyitlibrary.org/files/original/3b128ad6218a12bf418fbf496fd2ada6.pdf 715a59ed1e0918559e170c1742c5ab3f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Business Administration Thesis A long essay or dissertation involving personal research, written by a candidate for a college degree. School School of Business Administration Department Department of Business Administration Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource World Bank and International Monetary Fund : Impact on the World's Economy Creator An entity primarily responsible for making the resource Gelb, Wayne Date A point or period of time associated with an event in the lifecycle of the resource 1988 Publisher An entity responsible for making the resource available Old Westbury, N.Y. : New York Institute of Technology, 1988. 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Title A name given to the resource Business Administration - Dissertations & Theses Thesis A long essay or dissertation involving personal research, written by a candidate for a college degree. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Workload Recording : A Management Tool for the Clinical Laboratory Date A point or period of time associated with an event in the lifecycle of the resource 1985 Publisher An entity responsible for making the resource available New York Institute of Technology Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Text Creator An entity primarily responsible for making the resource Moos, Sanford J. Subject The topic of the resource Pathological laboratories--Management. Production standards. Identifier An unambiguous reference to the resource within a given context https://repository.nyitlibrary.org/files/original/3e3b4e43b786aa752ea506f4747bf404.pdf https://repository.nyitlibrary.org/files/original/3a43bc32bc783eaa21bd6e3724748c71.pdf 4babe1368d16eba92b07df693116e392 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Environmental Technology - Dissertations & Theses Thesis A long essay or dissertation involving personal research, written by a candidate for a college degree. School School of Engineering & Technology Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Worker Exposure to Various Hazardous Chemicals at Ruco Polymer Corp Creator An entity primarily responsible for making the resource Hui, Joseph S. Date A point or period of time associated with an event in the lifecycle of the resource 1995 Publisher An entity responsible for making the resource available New York Institute of Technology. Subject The topic of the resource Chemical industry--Law and legislation. Chemical workers--Health risk assessment. Hazardous substances--Health aspects. Language A language of the resource English. Format The file format, physical medium, or dimensions of the resource PDF. Type The nature or genre of the resource Thesis (M.S.)--New York Institute of Technology. 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Title A name given to the resource Work in progress : remediation of Chemical Waste Disposal Corporation. Creator An entity primarily responsible for making the resource Duckfield, Michael. Date A point or period of time associated with an event in the lifecycle of the resource 2001 Publisher An entity responsible for making the resource available New York Institute of Technology Subject The topic of the resource Hazardous waste site remediation. Hazardous wastes--Environmental aspects. 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For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Wordperfect 5.1 Training for On-The-Job Employees: Prepare a Basic Business Letter Creator An entity primarily responsible for making the resource Cheng, Hsiu-Feng Date A point or period of time associated with an event in the lifecycle of the resource 1991 Publisher An entity responsible for making the resource available New York Institute of Technology Subject The topic of the resource Commercial correspondence. Word processing. 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Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Word Processing : Fad or Fashion Creator An entity primarily responsible for making the resource Cattani, Debra Date A point or period of time associated with an event in the lifecycle of the resource 1980 Publisher An entity responsible for making the resource available New York Institute of Technology Subject The topic of the resource Word processing. 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Title A name given to the resource Women in Industrial Selling : Working in a Male Dominated Industry Publisher An entity responsible for making the resource available New York Institute of Technology Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context <a href="https://repository.nyitlibrary.org/files/original/a92b9824945b074c52b594a429a8aad8.pdf">https://repository.nyitlibrary.org/files/original/a92b9824945b074c52b594a429a8aad8.pdf</a> Creator An entity primarily responsible for making the resource Cali, Sue Date A point or period of time associated with an event in the lifecycle of the resource 1981 Subject The topic of the resource Selling--Industrial equipment. Women sales personnel. 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Title A name given to the resource Women in Business : Environmental Factors and Advancement Creator An entity primarily responsible for making the resource Blicht, Rhoda Date A point or period of time associated with an event in the lifecycle of the resource 1987 Publisher An entity responsible for making the resource available New York Institute of Technology Subject The topic of the resource Women executives--United States. Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context <a href="https://repository.nyitlibrary.org/files/original/7aa5d81cfe7a52326573f963ed75c506.pdf">https://repository.nyitlibrary.org/files/original/7aa5d81cfe7a52326573f963ed75c506.pdf</a> https://repository.nyitlibrary.org/files/original/830256e0716174ecca209eb7c1d9e553.pdf b0c66c24834e09ce418fd13572603039 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Communication Arts - Dissertations & Theses Thesis A long essay or dissertation involving personal research, written by a candidate for a college degree. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource WLIW/Channel 21 : Ascertainment of Community Problems, Needs and Interests Creator An entity primarily responsible for making the resource Mosetis, Athana Date A point or period of time associated with an event in the lifecycle of the resource 1978 Publisher An entity responsible for making the resource available New York Institute of Technology Subject The topic of the resource Educational television stations. Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Text Identifier An unambiguous reference to the resource within a given context <a href="https://repository.nyitlibrary.org/files/original/830256e0716174ecca209eb7c1d9e553.pdf">https://repository.nyitlibrary.org/files/original/830256e0716174ecca209eb7c1d9e553.pdf</a> Communication Arts Thesis https://repository.nyitlibrary.org/files/original/f747f357a2599675ba5a9fbe5eb5b33b.pdf 750daf609c3a4f4dbfefcc44dd7034aa Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Architecture & Design - Dissertations & Theses Thesis A long essay or dissertation involving personal research, written by a candidate for a college degree. School School of Architecture & Design Department Department of Architecture Degree Bachelors of Architecture B.Arch. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Within Reach Creator An entity primarily responsible for making the resource Nunez, Shanil Publisher An entity responsible for making the resource available Old Westbury, N.Y. : New York Institute of Technology, 2022 Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Thesis (Bachelor's)--New York Institute of Technology, 2022 Identifier An unambiguous reference to the resource within a given context https://repository.nyitlibrary.org/files/original/f747f357a2599675ba5a9fbe5eb5b33b.pdf Date A point or period of time associated with an event in the lifecycle of the resource 2022 Subject The topic of the resource Health Facilities-- Sierra Leone-- Planning Vernacular Architecture Source A related resource from which the described resource is derived New York Institute of Technology, 2022 Architecture & Design Caretaking Thesis https://repository.nyitlibrary.org/files/original/8bd945f4b54dfd60969c3d77c0c6f5ba.pdf fe4a158a1b9d52f4bf77259d7637b0e5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Architecture & Design - Dissertations & Theses Thesis A long essay or dissertation involving personal research, written by a candidate for a college degree. School School of Architecture & Design Department Department of Architecture Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Winery, Long Island Identifier An unambiguous reference to the resource within a given context https://repository.nyitlibrary.org/files/original/8bd945f4b54dfd60969c3d77c0c6f5ba.pdf Creator An entity primarily responsible for making the resource Marinello, Assunta Date A point or period of time associated with an event in the lifecycle of the resource 1995 Publisher An entity responsible for making the resource available Old Westbury, N.Y. : New York Institute of Technology Subject The topic of the resource Wineries—New York (State)—Long Island Language A language of the resource English Format The file format, physical medium, or dimensions of the resource PDF Type The nature or genre of the resource Thesis (Bachelor's)--New York Institute of Technology