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Tags: angiogenesis, antiinflammatory activity, astrocyte, brain metastasis, breast cancer, carcinomatous meningitis, central nervous system metastasis, cerebrospinal fluid analysis, circulating tumor DNA, follow up, gene expression profiling, gene mutation, genetic profile, human, immune response, immunotherapy, macrophage, malignant neoplasm, microglia, nonhuman, nuclear magnetic resonance imaging, positron emission tomography-computed tomography, Review, treatment planning, treatment response, tumor growth, tumor microenvironment, upregulation